Platelet concentrates: reducing the risk of transfusion-transmitted bacterial infections
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Platelet concentrates: reducing the risk of transfusion-transmitted bacterial infections
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Blood transmitted infection is the commonest cause of death after blood transfusion. All patients on regular packed cell volume (PCV) or any blood component are at increased risk of transfusion transmitted infections. The etiological agents can be virus, bacteria or protozoa. These organisms can cause clinical sickness in recipient, can persist in him as carrier state or can cause asymptomatic ...
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Before 1970, approximately 6% of multi-transfused recipients acquired a transfusion-transmitted Hepatitis B virus (HBV) infection. The safety improvements since then have been tremendous. From a level of a few infections per 1000 donations, the risk today, depending on the screening algorithm and additional measurements performed, has decreased to around 1:500,000 to 1:1,000,000, an improvement...
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Preventing transfusion-associated infections presents one of the greatest challenges of transfusion medicine. Thanks to the combination of strict selection of donors and consistent testing of each blood donation for infective pathogens using validated test procedures, the risk of transmission could be markedly reduced, especially since the most sensitive diagnostic method suitable for donor scr...
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Background & Aims: Today, an important challenge of the Blood Transfusion Organization is the preparation, distribution, and monitoring of the appropriate use of blood and blood products. Therefore, estimation of the prevalence of transfusion transmitted infections (TTIs) and efficiency of appropriate screening methods is essential. The purpose of the present study was the det...
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ژورنال
عنوان ژورنال: International Journal of Clinical Transfusion Medicine
سال: 2014
ISSN: 2253-3249
DOI: 10.2147/ijctm.s40037